Hand Piercings, Finger Piercings, and Hand Web piercings are all very rare and rather extreme. In fact, if you are even considering getting one of these piercings, you are truly one of the brave. The pain varies, and in fact usually there is minimal pain involved with the piercing, but the aftercare of these particular piercings is only for the stringent at heart.
Your hands are two of the most active places on your body. They are constantly in motion, they are full of germs, and they are very sensitive (all those nerves running through our hands help the brain process pain, pleasure, and temperatures). A contemporary phenomenon is getting the surfaces on your hands pierced. I'm not against these piercings at all, but more than most piercings, it is important you understand the risks before committing to the piercing.
Hand piercings are all surface piercings, so they are susceptible to the usual suspects - migration and rejection. Your hands are chock full of muscles, tendons, and nerves, so the constant motion of your hands don't exactly work in your favor. Generally, the less disturbed the piercing area, the quicker and more successful the healing. With hand piercings you will not have the luxury keeping a hand "protected". It will be exposed to the elements, germs, daily stresses, and abuses straightaway. For this reason, only get a hand piercing if you are willing to do the following.
First of all, you must clean it religiously. Your piercer will recommend cleaning it somewhere around three times a day with a warm saline solution - don't skip this step! The saline helps keep the piercing site clean and free of buildup. You will have special instructions concerning which soap you can use, what moisturizer you can use, what liquids or gels you can't put on your hands (Neosporin is always a no-no), ad infinitum. Smoking is definitely discouraged with a hand piercing, for the cigarette smoke that will inevitably drift around it will irritate your new piercing and prolong the healing. You must also be sure to keep the piercing site clean, not just from germs, but from dirt, trash, food, etc. Remember, you have a very delicate piercing that is being assaulted from all sides, so be careful!
Your lifestyle may have to change as well during the healing period. Besides not smoking, you shouldn't be wearing gloves (they can tear the piercings out) or engaging in any activity that may put your hands at risk. If your career heavily depends on using your hands, you may want to think about getting one of these piercings extra carefully. Your everyday life will be affected by this piercing for at least a year - which is the general healing time. If you've never had a body piercing before, this probably isn't a good one to start out with!
Now that the risks are known, and you still want to go ahead, here is what you can expect! For starters, don't get pierced with a ring or hoop. You are just begging for it to get ripped out! Your hands touch too many objects everyday and a ring jutting out will get snared on something and it will be gone before you know it. Your piercer and you will decide if surface bars or curved barbells are best for your piercing location (which is largely determined by the shape of your hands, exact location, and lifestyle). It is not uncommon to have to get refitted a couple months after the piercing, for the swelling should have gone down enough to where you might need new jewelry to lie closer to the skin.
For hand piercings, the location can be almost anywhere. Surface bars will almost always be used, and the pain might be a bit intense. Rejection risk is high since there is not a lot of skin or tissue to penetrate, but with care this can be a relatively long term piercing.
Finger piercings generally don't hurt nearly as much as they look, but these too have a high risk of migration. Generally pierced at the base of the finger to look like a ring, surface bars or barbells are used. The finger will swell after piercing, and is highly prone to infection, but by following the right aftercare and being super careful, you just may be able to make this piercing last a good long while.
Hand web piercings might be the most popular of the hand piercings - the webbing between each finger (especially between thumb and forefinger) is very thin and not hard to push a barbell through. It is also prone to rejection and migration, and infection is a very real possibility. This piercing should not affect your mobility (none of these piercings should affect any of your body functions), but the hand webs are major points in acupuncture therapy, so if you talk to an acupuncturist they probably won't be keen on you receiving a piercing this area. There's no western scientific evidence that piercing your hand webs will hurt you, but if you follow eastern medicine and science, you may want to hold off on web piercings.
All in all, piercings on the hand are rather extreme. They require constant care, zealous protection, regular cleaning, and even then it's not a guarantee that these piercings will last. Yet, if you want to push the boundaries and your lifestyle affords it, you can try to get a piercing on your hand. For many people who successfully have them, it's their favorite piercing